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CRISPR–Cas12a system in fission yeast for multiplex genomic editing and CRISPR interference
The CRISPR–Cas12a is a class II, type V clustered regularly interspaced short palindromic repeat (CRISPR) system with both RNase and DNase activity. Compared to the CRISPR–Cas9 system, it recognizes T-rich PAM sequences and has the advantage of multiplex genomic editing. Here, in fission yeast Schiz...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261154/ https://www.ncbi.nlm.nih.gov/pubmed/32374858 http://dx.doi.org/10.1093/nar/gkaa329 |