High specificity and tight spatial restriction of self-biotinylation by DNA and RNA G-Quadruplexes complexed in vitro and in vivo with Heme

Guanine-rich, single-stranded DNAs and RNAs that fold to G-quadruplexes (GQs) are able to complex tightly with heme and display strongly enhanced peroxidase activity. Phenolic compounds are particularly good substrates for these oxidative DNAzymes and ribozymes; we recently showed that the use of bi...

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Detalles Bibliográficos
Autores principales: Lat, Prince Kumar, Liu, Kun, Kumar, Dev N, Wong, Kenneth K L, Verheyen, Esther M, Sen, Dipankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261162/
https://www.ncbi.nlm.nih.gov/pubmed/32329781
http://dx.doi.org/10.1093/nar/gkaa281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261162/
https://www.ncbi.nlm.nih.gov/pubmed/32329781
http://dx.doi.org/10.1093/nar/gkaa281

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