Cargando…

Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions

Germline variations in immunoglobulin genes influence the repertoire of B cell receptors and antibodies, and such polymorphisms may impact disease susceptibility. However, the knowledge of the genomic variation of the immunoglobulin loci is scarce. Here, we report 25 potential novel germline IGHV al...

Descripción completa

Detalles Bibliográficos
Autores principales: Mikocziova, Ivana, Gidoni, Moriah, Lindeman, Ida, Peres, Ayelet, Snir, Omri, Yaari, Gur, Sollid, Ludvig M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261178/
https://www.ncbi.nlm.nih.gov/pubmed/32365177
http://dx.doi.org/10.1093/nar/gkaa310