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Spatial organization-dependent EphA2 transcriptional responses revealed by ligand nanocalipers

Ligand binding induces extensive spatial reorganization and clustering of the EphA2 receptor at the cell membrane. It has previously been shown that the nanoscale spatial distribution of ligands modulates EphA2 receptor reorganization, activation and the invasive properties of cancer cells. However,...

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Detalles Bibliográficos
Autores principales: Verheyen, Toon, Fang, Trixy, Lindenhofer, Dominik, Wang, Yang, Akopyan, Karen, Lindqvist, Arne, Högberg, Björn, Teixeira, Ana I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261182/
https://www.ncbi.nlm.nih.gov/pubmed/32352518
http://dx.doi.org/10.1093/nar/gkaa274