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Protein disorder-to-order transition enhances the nucleosome-binding affinity of H1

Intrinsically disordered proteins are crucial elements of chromatin heterogenous organization. While disorder in the histone tails enables a large variation of inter-nucleosome arrangements, disorder within the chromatin-binding proteins facilitates promiscuous binding to a wide range of different m...

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Detalles Bibliográficos
Autores principales: Sridhar, Akshay, Orozco, Modesto, Collepardo-Guevara, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261198/
https://www.ncbi.nlm.nih.gov/pubmed/32356891
http://dx.doi.org/10.1093/nar/gkaa285