Hepatitis B virus X protein promotes liver cell pyroptosis under oxidative stress through NLRP3 inflammasome activation

OBJECTIVE: Hepatitis B virus X protein (HBx) is a pivotal factor for HBV-induced hepatitis. Herein, we sought to investigate HBx-mediated NLR pyrin domain containing 3 (NLRP3) inflammasome activation and pyroptosis under oxidative stress. METHODS: The effect of HBx on the NLRP3 inflammasome was anal...

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Detalles Bibliográficos
Autores principales: Xie, Wen-hui, Ding, Jian, Xie, Xiao-xia, Yang, Xiao-huang, Wu, Xiao-Fan, Chen, Zhi-xin, Guo, Qi-lan, Gao, Wen-yu, Wang, Xiao-zhong, Li, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261280/
https://www.ncbi.nlm.nih.gov/pubmed/32347316
http://dx.doi.org/10.1007/s00011-020-01351-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261280/
https://www.ncbi.nlm.nih.gov/pubmed/32347316
http://dx.doi.org/10.1007/s00011-020-01351-z

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