Investigation of the reversibility of freeze/thaw stress-induced protein instability using heat cycling as a function of different cryoprotectants

ABSTRACT: Formulation conditions have a significant influence on the degree of freeze/thaw (FT) stress-induced protein instabilities. Adding cryoprotectants might stabilize the induced FT stress instabilities. However, a simple preservation of protein stability might be insufficient and further meth...

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Detalles Bibliográficos
Autores principales: Wöll, Anna K., Hubbuch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261286/
https://www.ncbi.nlm.nih.gov/pubmed/32198550
http://dx.doi.org/10.1007/s00449-020-02327-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261286/
https://www.ncbi.nlm.nih.gov/pubmed/32198550
http://dx.doi.org/10.1007/s00449-020-02327-3

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