Inhibition of P2X7 Purinergic Receptor Ameliorates Cardiac Fibrosis by Suppressing NLRP3/IL-1β Pathway

P2X7 purinergic receptor (P2X7R) has been implicated in several cardiovascular diseases. However, whether it regulates cardiac fibrosis remains elusive. Herein, its involvement in the development of cardiac fibrosis was examined using a transverse aortic constriction (TAC) mice model and cardiac fib...

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Detalles Bibliográficos
Autores principales: Zhou, Junteng, Tian, Geer, Quan, Yue, Li, Junli, Wang, Xiaojiao, Wu, Wenchao, Li, Miaoling, Liu, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261319/
https://www.ncbi.nlm.nih.gov/pubmed/32566102
http://dx.doi.org/10.1155/2020/7956274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261319/
https://www.ncbi.nlm.nih.gov/pubmed/32566102
http://dx.doi.org/10.1155/2020/7956274

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