High-Throughput Docking and Molecular Dynamics Simulations towards the Identification of Potential Inhibitors against Human Coagulation Factor XIIa

Human coagulation factor XIIa (FXIIa) is a trypsin-like serine protease that is involved in pathologic thrombosis. As a potential target for designing safe anticoagulants, FXIIa has received a great deal of interest in recent years. In the present study, we employed virtual high-throughput screening...

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Detalles Bibliográficos
Autores principales: Xu, Dongfang, Xue, Guangpu, Peng, Bangya, Feng, Zanjie, Lu, Hongling, Gong, Lihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261338/
https://www.ncbi.nlm.nih.gov/pubmed/32549905
http://dx.doi.org/10.1155/2020/2852051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261338/
https://www.ncbi.nlm.nih.gov/pubmed/32549905
http://dx.doi.org/10.1155/2020/2852051

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