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Inhibition of HIF1A-AS1 promoted starvation-induced hepatocellular carcinoma cell apoptosis by reducing HIF-1α/mTOR-mediated autophagy

BACKGROUND: Hepatocellular carcinoma (HCC) is still a major health burden in China considering its high incidence and mortality. Long non-coding RNAs (lncRNAs) were found playing vital roles in tumor progression, suggesting a new way of diagnosis and prognosis prediction, or treatment of HCC. This s...

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Detalles Bibliográficos
Autores principales: Hong, Fenfen, Gao, Yu, Li, Yang, Zheng, Linfeng, Xu, Feng, Li, Xianpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261383/
https://www.ncbi.nlm.nih.gov/pubmed/32473641
http://dx.doi.org/10.1186/s12957-020-01884-x