ISCU interacts with NFU1, and ISCU[4Fe-4S] transfers its Fe-S cluster to NFU1 leading to the production of holo-NFU1

NFU1 is a late-acting factor in the biogenesis of human mitochondrial iron-sulfur proteins. Mutations in NFU1 are associated with genetic diseases such as multiple mitochondrial dysfunctions syndrome 1 (MMDS1) that involve defects in mitochondrial [4Fe-4S] proteins. We present results from NMR spect...

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Detalles Bibliográficos
Autores principales: Cai, Kai, Frederick, Ronnie O., Markley, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261492/
https://www.ncbi.nlm.nih.gov/pubmed/32151725
http://dx.doi.org/10.1016/j.jsb.2020.107491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261492/
https://www.ncbi.nlm.nih.gov/pubmed/32151725
http://dx.doi.org/10.1016/j.jsb.2020.107491

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