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Measurement of hydroxychloroquine in blood from SLE patients using LC-HRMS—evaluation of whole blood, plasma, and serum as sample matrices

BACKGROUND: Hydroxychloroquine (HCQ) is the standard of care in the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and other inflammatory rheumatic diseases and potentially for the treatment in COVID-19 patients. Determination of HCQ for therapeutic drug monitoring (TDM)...

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Detalles Bibliográficos
Autores principales: Carlsson, Henrik, Hjorton, Karin, Abujrais, Sandy, Rönnblom, Lars, Åkerfeldt, Torbjörn, Kultima, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261520/
https://www.ncbi.nlm.nih.gov/pubmed/32475347
http://dx.doi.org/10.1186/s13075-020-02211-1