The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman  Pinschers of efficacy and outcomes

AIMS: Aptamer BC 007, a 15‐mer single‐strand DNA oligonucleotide (5'‐GGTTGGTGTGGTTGG‐3'), was developed to neutralize functional autoantibodies that bind to the extracellular domains of G protein‐coupled receptors (GPCR‐AAB), leading to the modulation of receptor‐mediated signalling cascad...

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Detalles Bibliográficos
Autores principales: Werner, Sabine, Wallukat, Gerd, Becker, Niels‐Peter, Wenzel, Katrin, Müller, Johannes, Schimke, Ingolf, Wess, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261533/
https://www.ncbi.nlm.nih.gov/pubmed/32212256
http://dx.doi.org/10.1002/ehf2.12628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261533/
https://www.ncbi.nlm.nih.gov/pubmed/32212256
http://dx.doi.org/10.1002/ehf2.12628

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