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The aptamer BC 007 for treatment of dilated cardiomyopathy: evaluation in Doberman Pinschers of efficacy and outcomes

AIMS: Aptamer BC 007, a 15‐mer single‐strand DNA oligonucleotide (5'‐GGTTGGTGTGGTTGG‐3'), was developed to neutralize functional autoantibodies that bind to the extracellular domains of G protein‐coupled receptors (GPCR‐AAB), leading to the modulation of receptor‐mediated signalling cascad...

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Detalles Bibliográficos
Autores principales:	Werner, Sabine, Wallukat, Gerd, Becker, Niels‐Peter, Wenzel, Katrin, Müller, Johannes, Schimke, Ingolf, Wess, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261533/ https://www.ncbi.nlm.nih.gov/pubmed/32212256 http://dx.doi.org/10.1002/ehf2.12628

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