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Saccharomyces cerevisiae ER membrane protein complex subunit 4 (EMC4) plays a crucial role in eIF2B-mediated translation regulation and survival under stress conditions

BACKGROUND: Eukaryotic initiation factor 2B (eIF2B) initiates and regulates translation initiation in eukaryotes. eIF2B gene mutations cause leukoencephalopathy called vanishing white matter disease (VWM) in humans and slow growth (Slg(−)) and general control derepression (Gcd(−)) phenotypes in Sacc...

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Detalles Bibliográficos
Autores principales: Sharma, Sonum, Sourirajan, Anuradha, Baumler, David J., Dev, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261713/
https://www.ncbi.nlm.nih.gov/pubmed/32476094
http://dx.doi.org/10.1186/s43141-020-00029-7