A short-term inhalation study to assess the reversibility of sensory irritation in human volunteers

Sensory irritation is an acute adverse effect caused by chemicals that stimulate chemoreceptors of the upper respiratory tract or the mucous membranes of the outer eye. The avoidance of this end point is of uttermost importance in regulatory toxicology. In this study, repeated exposures to ethyl acr...

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Detalles Bibliográficos
Autores principales: Kleinbeck, Stefan, Schäper, Michael, Pacharra, Marlene, Lehmann, Marie Louise, Golka, Klaus, Blaszkewicz, Meinolf, Brüning, Thomas, van Thriel, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Organ Toxicity and Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261732/
https://www.ncbi.nlm.nih.gov/pubmed/32185413
http://dx.doi.org/10.1007/s00204-020-02703-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261732/
https://www.ncbi.nlm.nih.gov/pubmed/32185413
http://dx.doi.org/10.1007/s00204-020-02703-8

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