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A short-term inhalation study to assess the reversibility of sensory irritation in human volunteers
Sensory irritation is an acute adverse effect caused by chemicals that stimulate chemoreceptors of the upper respiratory tract or the mucous membranes of the outer eye. The avoidance of this end point is of uttermost importance in regulatory toxicology. In this study, repeated exposures to ethyl acr...
Autores principales: | Kleinbeck, Stefan, Schäper, Michael, Pacharra, Marlene, Lehmann, Marie Louise, Golka, Klaus, Blaszkewicz, Meinolf, Brüning, Thomas, van Thriel, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261732/ https://www.ncbi.nlm.nih.gov/pubmed/32185413 http://dx.doi.org/10.1007/s00204-020-02703-8 |
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