Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with hormonal regulation of the breast

Knowledge about established breast carcinogens can support improved and modernized toxicological testing methods by identifying key mechanistic events. Ionizing radiation (IR) increases the risk of breast cancer, especially for women and for exposure at younger ages, and evidence overall supports a...

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Detalles Bibliográficos
Autores principales: Helm, Jessica S., Rudel, Ruthann A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261741/
https://www.ncbi.nlm.nih.gov/pubmed/32399610
http://dx.doi.org/10.1007/s00204-020-02752-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261741/
https://www.ncbi.nlm.nih.gov/pubmed/32399610
http://dx.doi.org/10.1007/s00204-020-02752-z

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