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The A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults

OBJECTIVE: To clarify the preclinical stage of Alzheimer’s disease by estimating when β‐amyloid accumulation first becomes associated with changes in cognition. METHODS: Here we studied a large group (N = 4432) of cognitively unimpaired individuals who were screened for inclusion in the A4 trial (ag...

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Detalles Bibliográficos
Autores principales: Insel, Philip S., Donohue, Michael C., Sperling, Reisa, Hansson, Oskar, Mattsson‐Carlgren, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261742/
https://www.ncbi.nlm.nih.gov/pubmed/32315118
http://dx.doi.org/10.1002/acn3.51048