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Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

The cytochrome P450 monooxygenase P450 BM3 (BM3) is a biotechnologically important and versatile enzyme capable of producing important compounds such as the medical drugs pravastatin and artemether, and the steroid hormone testosterone. BM3 is a natural fusion enzyme comprising two major domains: a...

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Detalles Bibliográficos
Autores principales: Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261786/
https://www.ncbi.nlm.nih.gov/pubmed/32303637
http://dx.doi.org/10.1074/jbc.RA119.011630