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Sphingosine kills bacteria by binding to cardiolipin

Sphingosine is a long-chain sphingoid base that has been shown to have bactericidal activity against many pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. We have previously demonstrated that sphingosine is present in nasal, tracheal, and bronchial epithelial...

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Detalles Bibliográficos
Autores principales: Verhaegh, Rabea, Becker, Katrin Anne, Edwards, Michael J., Gulbins, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261797/
https://www.ncbi.nlm.nih.gov/pubmed/32327486
http://dx.doi.org/10.1074/jbc.RA119.012325