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A randomized placebo-controlled PET study of ketamine´s effect on serotonin(1B) receptor binding in patients with SSRI-resistant depression

The glutamate N-methyl-d-aspartate receptor antagonist ketamine has a rapid antidepressant effect. Despite large research efforts, ketamine’s mechanism of action in major depressive disorder (MDD) has still not been determined. In rodents, the antidepressant properties of ketamine were found to be d...

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Detalles Bibliográficos
Autores principales: Tiger, Mikael, Veldman, Emma R., Ekman, Carl-Johan, Halldin, Christer, Svenningsson, Per, Lundberg, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261801/
https://www.ncbi.nlm.nih.gov/pubmed/32475989
http://dx.doi.org/10.1038/s41398-020-0844-4