Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses

Accumulation and propagation of hyperphosphorylated Tau (p-Tau) is a common neuropathological hallmark associated with neurodegeneration of Alzheimer's disease (AD), frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), and related tauopathies. Extracellular vesicles, spec...

Descripción completa

Detalles Bibliográficos
Autores principales: Podvin, Sonia, Jones, Alexander, Liu, Qing, Aulston, Brent, Ransom, Linnea, Ames, Janneca, Shen, Gloria, Lietz, Christopher B., Jiang, Zhenze, O'Donoghue, Anthony J., Winston, Charisse, Ikezu, Tsuneya, Rissman, Robert A., Yuan, Shauna, Hook, Vivian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261814/
https://www.ncbi.nlm.nih.gov/pubmed/32295833
http://dx.doi.org/10.1074/mcp.RA120.002079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261814/
https://www.ncbi.nlm.nih.gov/pubmed/32295833
http://dx.doi.org/10.1074/mcp.RA120.002079

Ejemplares similares