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Whole Genome Sequencing of Hepatitis A Virus Using a PCR-Free Single-Molecule Nanopore Sequencing Approach

Hepatitis A virus (HAV) is one of the most common causes of acute viral hepatitis in humans. Although HAV has a relatively small genome, there are several factors limiting whole genome sequencing such as PCR amplification artefacts and ambiguities in de novo assembly. The recently developed Oxford N...

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Detalles Bibliográficos
Autores principales: Batista, Frederico M., Stapleton, Tina, Lowther, James A., Fonseca, Vera G., Shaw, Rebecca, Pond, Christopher, Walker, David I., van Aerle, Ronny, Martinez-Urtaza, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261825/
https://www.ncbi.nlm.nih.gov/pubmed/32523561
http://dx.doi.org/10.3389/fmicb.2020.00874