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Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms

Biofilms formed by the fungal pathogen Candida albicans are resistant to many of the antifungal agents commonly used in the clinic. Previous reports suggest that protease inhibitors, specifically inhibitors of aspartyl proteases, could be effective antibiofilm agents. We screened three protease inhi...

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Detalles Bibliográficos
Autores principales: Lohse, Matthew B., Gulati, Megha, Craik, Charles S., Johnson, Alexander D., Nobile, Clarissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261846/
https://www.ncbi.nlm.nih.gov/pubmed/32523574
http://dx.doi.org/10.3389/fmicb.2020.01027