Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator

AIMS: Our aim was to investigate the effect of nitric oxide (NO)-independent activation of soluble guanylyl cyclase (sGC) on cardiomyocyte function in a hypertensive animal model with diastolic dysfunction and in biopsies from human heart failure with preserved ejection fraction (HFpEF). METHODS: Da...

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Detalles Bibliográficos
Autores principales: Kolijn, Detmar, Kovács, Árpád, Herwig, Melissa, Lódi, Mária, Sieme, Marcel, Alhaj, Abdulatif, Sandner, Peter, Papp, Zoltán, Reusch, Peter H., Haldenwang, Peter, Falcão-Pires, Ines, Linke, Wolfgang A., Jaquet, Kornelia, Van Linthout, Sophie, Mügge, Andreas, Tschöpe, Carsten, Hamdani, Nazha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261855/
https://www.ncbi.nlm.nih.gov/pubmed/32523538
http://dx.doi.org/10.3389/fphys.2020.00345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261855/
https://www.ncbi.nlm.nih.gov/pubmed/32523538
http://dx.doi.org/10.3389/fphys.2020.00345

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