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Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator
AIMS: Our aim was to investigate the effect of nitric oxide (NO)-independent activation of soluble guanylyl cyclase (sGC) on cardiomyocyte function in a hypertensive animal model with diastolic dysfunction and in biopsies from human heart failure with preserved ejection fraction (HFpEF). METHODS: Da...
Autores principales: | Kolijn, Detmar, Kovács, Árpád, Herwig, Melissa, Lódi, Mária, Sieme, Marcel, Alhaj, Abdulatif, Sandner, Peter, Papp, Zoltán, Reusch, Peter H., Haldenwang, Peter, Falcão-Pires, Ines, Linke, Wolfgang A., Jaquet, Kornelia, Van Linthout, Sophie, Mügge, Andreas, Tschöpe, Carsten, Hamdani, Nazha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261855/ https://www.ncbi.nlm.nih.gov/pubmed/32523538 http://dx.doi.org/10.3389/fphys.2020.00345 |
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