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Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells

Peripheral inflammatory hyperalgesia depends on the sensitization of primary nociceptive neurons. Inflammation drives molecular alterations not only locally but also in the dorsal root ganglion (DRG) where interleukin-1 beta (IL-1β) and purinoceptors are upregulated. Activation of the P2X7 purinocep...

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Detalles Bibliográficos
Autores principales: Neves, Amanda Ferreira, Farias, Felipe Hertzing, de Magalhães, Silviane Fernandes, Araldi, Dionéia, Pagliusi, Marco, Tambeli, Claudia Herrera, Sartori, Cesar Renato, Lotufo, Celina Monteiro da Cruz, Parada, Carlos Amílcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261868/
https://www.ncbi.nlm.nih.gov/pubmed/32523543
http://dx.doi.org/10.3389/fphys.2020.00473