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Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells
Peripheral inflammatory hyperalgesia depends on the sensitization of primary nociceptive neurons. Inflammation drives molecular alterations not only locally but also in the dorsal root ganglion (DRG) where interleukin-1 beta (IL-1β) and purinoceptors are upregulated. Activation of the P2X7 purinocep...
Autores principales: | Neves, Amanda Ferreira, Farias, Felipe Hertzing, de Magalhães, Silviane Fernandes, Araldi, Dionéia, Pagliusi, Marco, Tambeli, Claudia Herrera, Sartori, Cesar Renato, Lotufo, Celina Monteiro da Cruz, Parada, Carlos Amílcar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261868/ https://www.ncbi.nlm.nih.gov/pubmed/32523543 http://dx.doi.org/10.3389/fphys.2020.00473 |
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