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A Trispecific Anti-HIV Chimeric Antigen Receptor Containing the CCR5 N-Terminal Region

Anti-HIV chimeric antigen receptors (CARs) promote direct killing of infected cells, thus offering a therapeutic approach aimed at durable suppression of infection emerging from viral reservoirs. CD4-based CARs represent a favored option, since they target the essential conserved primary receptor bi...

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Detalles Bibliográficos
Autores principales: Hajduczki, Agnes, Danielson, David T., Elias, David S., Bundoc, Virgilio, Scanlan, Aaron W., Berger, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261873/
https://www.ncbi.nlm.nih.gov/pubmed/32523897
http://dx.doi.org/10.3389/fcimb.2020.00242