Concerted Action of AMPK and Sirtuin-1 Induces Mitochondrial Fragmentation Upon Inhibition of Ca(2+) Transfer to Mitochondria

Mitochondria are highly dynamic organelles constantly undergoing fusion and fission. Ca(2+) regulates many aspects of mitochondrial physiology by modulating the activity of several mitochondrial proteins. We previously showed that inhibition of constitutive IP3R-mediated Ca(2+) transfer to the mitoc...

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Detalles Bibliográficos
Autores principales: Lovy, Alenka, Ahumada-Castro, Ulises, Bustos, Galdo, Farias, Paula, Gonzalez-Billault, Christian, Molgó, Jordi, Cardenas, Cesar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261923/
https://www.ncbi.nlm.nih.gov/pubmed/32523953
http://dx.doi.org/10.3389/fcell.2020.00378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261923/
https://www.ncbi.nlm.nih.gov/pubmed/32523953
http://dx.doi.org/10.3389/fcell.2020.00378

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