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Concerted Action of AMPK and Sirtuin-1 Induces Mitochondrial Fragmentation Upon Inhibition of Ca(2+) Transfer to Mitochondria
Mitochondria are highly dynamic organelles constantly undergoing fusion and fission. Ca(2+) regulates many aspects of mitochondrial physiology by modulating the activity of several mitochondrial proteins. We previously showed that inhibition of constitutive IP3R-mediated Ca(2+) transfer to the mitoc...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261923/ https://www.ncbi.nlm.nih.gov/pubmed/32523953 http://dx.doi.org/10.3389/fcell.2020.00378 |