Therapeutic Targeting of Proteostasis in Amyotrophic Lateral Sclerosis—a Systematic Review and Meta-Analysis of Preclinical Research

Background: Amyotrophic lateral sclerosis (ALS) is a rapidly progressive fatal neurodegenerative condition. There are no effective treatments. The only globally licensed medication, that prolongs life by 2–3 months, was approved by the FDA in 1995. One reason for the absence of effective treatments...

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Detalles Bibliográficos
Autores principales: Elliott, Elizabeth, Bailey, Olivia, Waldron, Fergal M., Hardingham, Giles E., Chandran, Siddharthan, Gregory, Jenna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261930/
https://www.ncbi.nlm.nih.gov/pubmed/32523508
http://dx.doi.org/10.3389/fnins.2020.00511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261930/
https://www.ncbi.nlm.nih.gov/pubmed/32523508
http://dx.doi.org/10.3389/fnins.2020.00511

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