The acidic tail of HMGB1 regulates its secondary structure and conformational flexibility: A circular dichroism and molecular dynamics simulation study

High mobility group box 1 (HMGB1) is a damage-associated molecular pattern (DAMP) molecule that triggers the progression of several pro-inflammatory diseases such as diabetes, Alzheimer’s disease and cancer, by inducing signals upon interaction with the receptors such as the receptor for advanced gl...

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Detalles Bibliográficos
Autores principales: Anggayasti, Wresti L., Ogino, Kenta, Yamamoto, Eiji, Helmerhorst, Erik, Yasuoka, Kenji, Mancera, Ricardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261955/
https://www.ncbi.nlm.nih.gov/pubmed/32514327
http://dx.doi.org/10.1016/j.csbj.2020.05.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261955/
https://www.ncbi.nlm.nih.gov/pubmed/32514327
http://dx.doi.org/10.1016/j.csbj.2020.05.012

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