Changes in PGC‐1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive impairment that increasingly afflicts the elderly population. Soluble oligomers (AβOs) has been implicated in AD pathogenesis: however, the molecular events underlying a role for Aβ are not well understood. We s...

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Detalles Bibliográficos
Autores principales: Panes, Jessica D., Godoy, Pamela A., Silva-Grecchi, Tiare, Celis, María T., Ramirez-Molina, Oscar, Gavilan, Javiera, Muñoz-Montecino, Carola, Castro, Patricio A., Moraga-Cid, Gustavo, Yévenes, Gonzalo E., Guzmán, Leonardo, Salisbury, Jeffrey L., Trushina, Eugenia, Fuentealba, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261959/
https://www.ncbi.nlm.nih.gov/pubmed/32523530
http://dx.doi.org/10.3389/fphar.2020.00709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261959/
https://www.ncbi.nlm.nih.gov/pubmed/32523530
http://dx.doi.org/10.3389/fphar.2020.00709

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