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Ritonavir and Lopinavir Suppress RCE1 and CAAX Rab Proteins Sensitizing the Liver to Organelle Stress and Injury

Organelle stress and Liver injuries often occur in human immunodeficiency virus (HIV) infected patients under anti‐HIV therapies, yet few molecular off‐targets of anti‐HIV drugs have been identified in the liver. Here, we found through total RNA sequencing that the transcription of a host protease R...

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Detalles Bibliográficos
Autores principales: Khalatbari, Atousa, Mishra, Pratibha, Han, Hui, He, Yuxin, MacVeigh‐Aloni, Michelle, Ji, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262282/
https://www.ncbi.nlm.nih.gov/pubmed/32490327
http://dx.doi.org/10.1002/hep4.1515