Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon‐α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus

RG7834 is a small‐molecule inhibitor of hepatitis B virus (HBV) gene expression that significantly reduces the levels of hepatitis B surface antigen (HBsAg) and HBV DNA in a humanized liver HBV mouse model. In the current study, we evaluated the potency of RG7834 in the woodchuck model of chronic HB...

Descripción completa

Detalles Bibliográficos
Autores principales: Menne, Stephan, Wildum, Steffen, Steiner, Guido, Suresh, Manasa, Korolowicz, Kyle, Balarezo, Maria, Yon, Changsuek, Murreddu, Marta, Hong, Xupeng, Kallakury, Bhaskar V., Tucker, Robin, Yang, Song, Young, John A.T., Javanbakht, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262289/
https://www.ncbi.nlm.nih.gov/pubmed/32490326
http://dx.doi.org/10.1002/hep4.1502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262289/
https://www.ncbi.nlm.nih.gov/pubmed/32490326
http://dx.doi.org/10.1002/hep4.1502

Ejemplares similares