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CSF levels of synaptosomal-associated protein 25 and synaptotagmin-1 in first-episode psychosis subjects

Post-mortem studies consistently show evidence of reduced synaptic protein levels in patients with schizophrenia. Clinically high-risk subjects show a steeper decrease in grey matter thickness and in vitro modeling using patient-derived cells implicate excessive synaptic pruning during neurodevelopm...

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Detalles Bibliográficos
Autores principales: Xu, Chengai, Sellgren, Carl M., Fatouros-Bergman, Helena, Piehl, Fredrik, Blennow, Kaj, Zetterberg, Henrik, Brinkmalm, Ann, Santillo, Alexander Frizell, Lundgren, Sofia, Cervenka, Simon, Engberg, Göran, Erhardt, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262376/
https://www.ncbi.nlm.nih.gov/pubmed/32490278
http://dx.doi.org/10.1016/j.ibror.2020.04.001