Quantitative Measurements of LRRK2 in Human Cerebrospinal Fluid Demonstrates Increased Levels in G2019S Patients

Leucine-rich repeat kinase 2 (LRRK2) mutations are among the most significant genetic risk factors for developing late onset Parkinson’s disease (PD). To understand whether a therapeutic can modulate LRRK2 levels as a potential disease modifying strategy, it is important to have methods in place to...

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Detalles Bibliográficos
Autores principales: Mabrouk, Omar S., Chen, Siwei, Edwards, Amanda L., Yang, Minhua, Hirst, Warren D., Graham, Danielle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262382/
https://www.ncbi.nlm.nih.gov/pubmed/32523511
http://dx.doi.org/10.3389/fnins.2020.00526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262382/
https://www.ncbi.nlm.nih.gov/pubmed/32523511
http://dx.doi.org/10.3389/fnins.2020.00526

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