Radioprotection of thymine and calf thymus DNA by an azo compound: mechanism of action followed by DPPH radical quenching & ROS depletion in WI 38 lung fibroblast cells

PURPOSE: To explain the observed radio-protection properties of an azo compound, 2-(2-hydroxyphenylazo)-indole-3(∕)-acetic acid (HPIA). MATERIALS AND METHODS: Mechanism of radioprotection by HPIA was attempted using the stable free radical 2, 2-diphenyl-1-picrylhydrazyl (DPPH) using UV-Vis and elect...

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Detalles Bibliográficos
Autores principales: Ganguly, Durba, Chandra Santra, Ramesh, Mazumdar, Swagata, Saha, Abhijit, Karmakar, Parimal, Das, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262411/
https://www.ncbi.nlm.nih.gov/pubmed/32490245
http://dx.doi.org/10.1016/j.heliyon.2020.e04036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262411/
https://www.ncbi.nlm.nih.gov/pubmed/32490245
http://dx.doi.org/10.1016/j.heliyon.2020.e04036

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