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Interferon-γ and voriconazole combined therapy for refractory meningeal coccidioidomycosis in a patient with interferon-γ deficiency

Coccidioides meningitis (CM) is a challenging infection, given the limited penetration to the cerebrospinal fluid of conventional antifungals, resulting in a high risk of recurrence. We present the first case of a successfully treated persistent CM with voriconazole and adjuvant INF-γ 1b.

Detalles Bibliográficos
Autores principales: De la Hoz, Alejandro, Malek, Alexandre, Hasbun, Rodrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262437/
https://www.ncbi.nlm.nih.gov/pubmed/32489879
http://dx.doi.org/10.1016/j.idcr.2020.e00835