Nanoparticle-Mediated Inhibition of Notch Signaling Promotes Mitochondrial Biogenesis and Reduces Subcutaneous Adipose Tissue Expansion in Pigs

Inhibition of Notch signaling has been shown to induce white to beige transformation of adipocytes and reduce the risk of obesity in mice. However, it remains unknown whether the metabolic benefits of Notch inhibition are dependent on uncoupling protein 1 (UCP1)-mediated thermogenesis and evolutiona...

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Detalles Bibliográficos
Autores principales: Huang, Di, Narayanan, Naagarajan, Cano-Vega, Mario A., Jia, Zhihao, Ajuwon, Kolapo M., Kuang, Shihuan, Deng, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262558/
https://www.ncbi.nlm.nih.gov/pubmed/32480124
http://dx.doi.org/10.1016/j.isci.2020.101167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262558/
https://www.ncbi.nlm.nih.gov/pubmed/32480124
http://dx.doi.org/10.1016/j.isci.2020.101167

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