Nuclear actin regulates cell proliferation and migration via inhibition of SRF and TEAD

Actin dynamics regulate cell behaviour in response to physiological signals. Here we demonstrate a novel role for nuclear actin in inhibiting cell proliferation and migration. We demonstrate that physiological signals that elevate cAMP, which is anti-mitogenic in vascular smooth muscle cells, increa...

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Detalles Bibliográficos
Autores principales: McNeill, Madeleine C., Wray, Jason, Sala-Newby, Graciela B., Hindmarch, Charles C.T., Smith, Sarah A., Ebrahimighaei, Reza, Newby, Andrew C., Bond, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262588/
https://www.ncbi.nlm.nih.gov/pubmed/32119877
http://dx.doi.org/10.1016/j.bbamcr.2020.118691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262588/
https://www.ncbi.nlm.nih.gov/pubmed/32119877
http://dx.doi.org/10.1016/j.bbamcr.2020.118691

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