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A mathematical model shows macrophages delay Staphylococcus aureus replication, but limitations in microbicidal capacity restrict bacterial clearance

S. aureus is a leading cause of bacterial infection. Macrophages, the first line of defence in the human immune response, phagocytose and kill S. aureus but the pathogen can evade these responses. Therefore, the exact role of macrophages is incompletely defined. We develop a mathematical model of ma...

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Detalles Bibliográficos
Autores principales: Best, Alex, Jubrail, Jamil, Boots, Mike, Dockrell, David, Marriott, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262596/
https://www.ncbi.nlm.nih.gov/pubmed/32304686
http://dx.doi.org/10.1016/j.jtbi.2020.110256