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Prophase-Specific Perinuclear Actin Coordinates Centrosome Separation and Positioning to Ensure Accurate Chromosome Segregation

Centrosome separation in late G2/ early prophase requires precise spatial coordination that is determined by a balance of forces promoting and antagonizing separation. The major effector of centrosome separation is the kinesin Eg5. However, the identity and regulation of Eg5-antagonizing forces is l...

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Detalles Bibliográficos
Autores principales: Stiff, Tom, Echegaray-Iturra, Fabio R., Pink, Harry J., Herbert, Alex, Reyes-Aldasoro, Constantino Carlos, Hochegger, Helfrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262599/
https://www.ncbi.nlm.nih.gov/pubmed/32460023
http://dx.doi.org/10.1016/j.celrep.2020.107681