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FTY720 Suppresses Liver Tumor Growth and Metastasis by Reducing Circulating Regulating T Cells and Enhancing the Anti-Tumor Effect of Rapamycin

BACKGROUND: In this study, we aimed to study the effect of FTY720 treatment in reducing circulating Tregs level and then suppressing liver tumor metastasis after hepatectomy and I/R injury in animal models. Furthermore, we also investigated the synergistic anti-tumor effect of FTY720 combined with r...

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Detalles Bibliográficos
Autores principales: Li, Chang Xian, Yang, Xin Xiang, Wang, Hong Wei, Li, Xiang Cheng, Ng, Kevin Tak-Pan, Lo, Chung Mau, Man, Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262652/
https://www.ncbi.nlm.nih.gov/pubmed/32547103
http://dx.doi.org/10.2147/OTT.S234394