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Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem Cells

Fetal hematopoietic stem cells (HSCs) undergo a developmental switch to become adult HSCs with distinct functional properties. To better understand the molecular mechanisms underlying the developmental switch, we have conducted deep sequencing of the 3D genome, epigenome, and transcriptome of fetal...

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Detalles Bibliográficos
Autores principales: Chen, Changya, Yu, Wenbao, Tober, Joanna, Gao, Peng, He, Bing, Lee, Kiwon, Trieu, Tuan, Blobel, Gerd A., Speck, Nancy A., Tan, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262670/
https://www.ncbi.nlm.nih.gov/pubmed/31851943
http://dx.doi.org/10.1016/j.celrep.2019.11.065