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Microglia depletion fails to abrogate inflammation-induced sickness in mice and rats
BACKGROUND: Production of inflammatory mediators by reactive microglial cells in the brain is generally considered the primary mechanism underlying the development of symptoms of sickness in response to systemic inflammation. METHODS: Depletion of microglia was achieved in C57BL/6 mice by chronic or...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262755/ https://www.ncbi.nlm.nih.gov/pubmed/32475344 http://dx.doi.org/10.1186/s12974-020-01832-2 |