Exosome miR‐27a‐3p secreted from adipocytes targets ICOS to promote antitumor immunity in lung adenocarcinoma

BACKGROUND: The clinical benefit of immunotherapy has been limited to a small subset of patients with cancer. Several clinical trials with immune checkpoint inhibitors in multiple cancers have shown some improvement in obese patients. However, how obesity regulates the immune microenvironment remain...

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Detalles Bibliográficos
Autores principales: Fan, Xuehan, Wang, Jingya, Qin, Tingting, Zhang, Yujia, Liu, Wenting, Jiang, Kaiting, Huang, Dingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262893/
https://www.ncbi.nlm.nih.gov/pubmed/32212417
http://dx.doi.org/10.1111/1759-7714.13411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262893/
https://www.ncbi.nlm.nih.gov/pubmed/32212417
http://dx.doi.org/10.1111/1759-7714.13411

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