Astrocytes in Atp1a2‐deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression

The ATP1A2 coding α2 subunit of Na,K‐ATPase, which is predominantly located in astrocytes, is a causative gene of familial hemiplegic migraine type 2 (FHM2). FHM2 model mice (Atp1a2(tmCKwk/+)) are susceptible to cortical spreading depression (CSD), which is profoundly related to migraine aura and he...

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Detalles Bibliográficos
Autores principales: Sugimoto, Hiroki, Sato, Masaaki, Nakai, Junichi, Kawakami, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262908/
https://www.ncbi.nlm.nih.gov/pubmed/32237043
http://dx.doi.org/10.1002/2211-5463.12848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262908/
https://www.ncbi.nlm.nih.gov/pubmed/32237043
http://dx.doi.org/10.1002/2211-5463.12848

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